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This is a list of genes considered to be realted too and not directly involved in drug metabolism. They include genes such as drug targets and receptors that are involved with the pharmacodynamic responses of drugs.

ADME Related Gene List 

 

Gene Symbol

                            Full Gene Name

ABP1

amiloride binding protein 1 (amine oxidase (copper-containing))

AKAP9

A kinase (PRKA) anchor protein (yotiao) 9,cytochrome P450, family 51, subfamily A, polypeptide 1

ALB

Albumin

APOA2

apolipoprotein A-II

ARS2

ARS2 protein

ARVCF

armadillo repeat gene deletes in velocardiofacial syndrome

ASNA1

arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)

ATG9B

ATG9 autophagy related 9 homolog B (S. cerevisiae)

BDH2

3-hydroxybutyrate dehydrogenase, type 2

BHLHB5

basic helix-loop-helix domain containing, class B, 5

C3orf15

chromosome 3 open reading frame 15      3q12-q13.3

C3orf36

chromosome 3 open reading frame 36

CCBP2

chemokine binding protein 2

CCBP2

chemokine binding protein 2

CDKN1C

cyclin-dependent kinase inhibitor 1C (p57, Kip2)

CHRNA2

cholinergic receptor, nicotinic, alpha 2 (neuronal) 

COL18A1

collagen, type XVIII, alpha 1 

COMT

catechol-O-methyltransferase

CREBL1

cAMP responsive element binding protein-like 1 

CROT

carnitine O-octanoyltransferase

CRYZ

crystallin, zeta (quinone reductase)

CTSK

cathepsin K

DNTTIP2

deoxynucleotidyltransferase, terminal, interacting protein 2

EAF2

ELL associated factor 2 3q21.1

EXOC6

exocyst complex component 6

FAM82A

family with sequence similarity 82, member A 

FAM82A

family with sequence similarity 82, member A 

FCER1G

Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide

G0S2

G0/G1switch 2 

G6PD

glucose-6-phosphate dehydrogenase

GCLC

glutamate-cysteine ligase, catalytic subunit 

GCLM

glutamate-cysteine ligase, modifier subunit 

GPLD1

glycosylphosphatidylinositol specific phospholipase D1

HLA-DOB

major histocompatibility complex, class II, DO beta

HLA-DOB

major histocompatibility complex, class II, DO beta

HMGCR

3-hydroxy-3-methylglutaryl-Coenzyme A reductase

HNRPA3

heterogeneous nuclear ribonucleoprotein A3

IGF2R

insulin-like growth factor 2 receptor

INTS12

integrator complex subunit 12

LOC133308

Na+/H+ exchanger domain containing 2

LPAL2

lipoprotein, Lp(a)-like 2 precursor

MAOA

monoamine oxidase A

MAOB

monoamine oxidase B

NFE2L2

nuclear factor (erythroid-derived 2)-like 2 

NHLRC1

NHL repeat containing 1

NQO1

NAD(P)H dehydrogenase, quinone 1

NR3C1

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

ORM1

orosomucoid 1 

ORM2

orosomucoid 2

PKD2

polycystic kidney disease 2

PLG

plasminogen

PPP1R9A

protein phosphatase 1, regulatory (inhibitor) subunit 9A

PRKAB2

protein kinase, AMP-activated, beta 2 non-catalytic subunit

PSMB8

proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)

PTGIS

prostaglandin I2 (prostacyclin) synthase

RALBP1

ralA binding protein 1

SGOL2

shugoshin-like 2 (S. pombe)

SHBG

sex hormone-binding globulin 

SPG7

spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive)

SRD5A2

3-oxo-5 alpha-steroid 4-dehydrogenase 2

STK19

serine/threonine kinase 19 isoform 1

TBXAS1

thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A)

TMEM63A

transmembrane protein 63A

TNIP1

TNFAIP3 interacting protein 1

TOMM40L

translocase of outer mitochondrial membrane 40

TPSG1

tryptase gamma 1

TSPO

translocator protein (18kDa)

TTBK1

tau tubulin kinase 1

TTR

 transthyretin (prealbumin, amyloidosis type I) 

TYMS

thymidylate synthetase

UNC93B1

unc-93 homolog B1

UROC1

urocanase domain containing 1

VKORC1

vitamin K epoxide reductase complex, subunit 1

ZBED1

Ac-like transposable element

 

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